En cuestión¿Reemplazar dinámicamente el contenido de un método C #? Encontré una buena respuesta de @ Logman. No tengo derecho a preguntarlo en los comentarios.

using System;
using System.Reflection;
using System.Runtime.CompilerServices;

namespace ReplaceHandles
{
    class Program
    {
        static void Main(string[] args)
        {
            Injection.replace();
            Target target = new Target();
            target.test();
            Console.Read();
        }
    }

    public class Injection
    {
        public static void replace()
        {
            MethodInfo methodToReplace = typeof(Target).GetMethod("test", BindingFlags.Instance | BindingFlags.Static | BindingFlags.NonPublic | BindingFlags.Public);
            MethodInfo methodToInject = typeof(Target2).GetMethod("test", BindingFlags.Instance | BindingFlags.Static | BindingFlags.NonPublic | BindingFlags.Public);
            RuntimeHelpers.PrepareMethod(methodToReplace.MethodHandle);
            RuntimeHelpers.PrepareMethod(methodToInject.MethodHandle);
            ReplaceInner(methodToReplace, methodToInject);
        }

        static void ReplaceInner(MethodInfo methodToReplace, MethodInfo methodToInject)
        {
            unsafe
            {
                if (IntPtr.Size == 4)
                {
                    int* inj = (int*)methodToInject.MethodHandle.Value.ToPointer() + 2;
                    int* tar = (int*)methodToReplace.MethodHandle.Value.ToPointer() + 2;
                    *tar = *inj;
                }
                else
                {
                    ulong* inj = (ulong*)methodToInject.MethodHandle.Value.ToPointer() + 1;
                    ulong* tar = (ulong*)methodToReplace.MethodHandle.Value.ToPointer() + 1;
                    *tar = *inj;
                }
            }
        }
    }


    public class Base
    {
        public virtual void test()
        {

        }
    }

    public class Target : Base
    {
        public override void test()
        {
            Console.WriteLine("Target.test()");
        }

        public void test3()
        {
            Console.WriteLine("Target.test3()");
        }
    }

    public class Target2
    {
        public void test()
        {
            Console.WriteLine("Target.test2()");
        }
    }
}

Todo funciona, pero no funciona la sustitución de métodos anulados.